Discovering and detecting transposable elements in genome sequences
نویسندگان
چکیده
منابع مشابه
Discovering and detecting transposable elements in genome sequences
The contribution of transposable elements (TEs) to genome structure and evolution as well as their impact on genome sequencing, assembly, annotation and alignment has generated increasing interest in developing new methods for their computational analysis. Here we review the diversity of innovative approaches to identify and annotate TEs in the post-genomic era, covering both the discovery of n...
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Transposable elements (TEs) are mobile, repetitive sequences that make up significant fractions of metazoan genomes. Despite their near ubiquity and importance in genome and chromosome biology, most efforts to annotate TEs in genome sequences rely on the results of a single computational program, RepeatMasker. In contrast, recent advances in gene annotation indicate that high-quality gene model...
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The nature of the role played by mobile elements in host genome evolution is reassessed considering numerous recent developments in many areas of biology. It is argued that easy popular appellations such as ‘‘selfish DNA’’ and ‘‘junk DNA’’ may be either inaccurate or misleading and that a more enlightened view of the transposable element-host relationship encompasses a continuum from extreme pa...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2007
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbm048